Jiandong (Dongdong) Huo

Current team member

After completing an undergraduate degree in Medical Microbiology & Immunology at Newcastle University, I joined the T-cell biology group in 2008 to start my D. Phil, funded by the Clarendon fund and a Nuffield Department of Clinical Medicine (NDM) Research Prize, and obtained my degree in 2012.

Working in the T-cell biology group is a completely different experience for me. My previous research experience involved functional studies of a cell wall protein and a cellular protein in Bacillus subtilis (an experimental system for Gram-Positive bacteria), in Prof. Errington’s group.

My current work focuses on investigating the first stage of the intracellular signaling network in T cells, i.e. the binding of SH2-domain containing proteins to the phosphorylated cytoplasmic tails of cell surface receptors, aiming to build up a systemic model of the network of such interactions in a T cell.