Hussain Abidi
Originally from Pakistan, Hussain was keen to study for his PhD at a top UK university. He applied to several labs in Oxford and Cambridge, and visited the UK to visit the labs and their professors.
Hussain was attracted to the Davis Lab by the quality of the work – apparent by the quality of the journals in which the lab’s papers were published.
“The research was top-notch and Simon publishes at the top of his field in high-impact journals. This was my main reason for choosing to work with him.” – Hussain
As an overseas student, Hussain found the team at the WIMM invaluable in helping him settle in.
Unusually for a lab, there is a strong social element, with an opportunity for everyone to socialise and get to know each other outside of the lab.
He was impressed how Simon expects his students, even the new ones, to contribute and share their ideas.
“I already knew what kind of work I wanted to do and the lab’s research interests aligned with my own. Everyone in the lab was really happy and welcoming.” – Hussain.
After studying for his PhD under Simon’s direction, Hussain moved to the US where he studied at Harvard Medical School for one year followed by post-doc research. He is now CEO of his own Biotech Startup in Boston, MA.
Top Ten Papers
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A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer
James JR, Oliveira MI, Carmo AM, Iaboni A, Davis SJ. (2006), Nat Methods. 3, 1001-6
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Crystal structure of a soluble CD28-Fab complex
Evans EJ, Esnouf RM, Manso-Sancho R, Gilbert RJ, James JR, Yu C, Fennelly JA, Vowles C, Hanke T, Walse B, Hünig T, Sørensen P, Stuart DI, Davis SJ. (2005), Nat Immunol. 6, 271-9
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The T cell surface – how well do we know it?
Evans EJ, Hene L, Sparks LM, Dong T, Retiere C, Fennelly JA, Manso-Sancho R, Powell J, Braud VM, Rowland-Jones SL, McMichael AJ, Davis SJ. (2003), Immunity. 19, 213-23
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The interaction properties of costimulatory molecules revisited
Collins AV, Brodie DW, Gilbert RJ, Iaboni A, Manso-Sancho R, Walse B, Stuart DI, van der Merwe PA, Davis SJ. (2002), Immunity. 17, 201-10
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LICOS, a primordial costimulatory ligand?
Brodie D, Collins AV, Iaboni A, Fennelly JA, Sparks LM, Xu XN, van der Merwe PA, Davis SJ. (2000), Curr Biol. 10, 333-6
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Structure and dimerization of a soluble form of B7-1
Ikemizu S, Gilbert RJ, Fennelly JA, Collins AV, Harlos K, Jones EY, Stuart DI, Davis SJ. (2000), Immunity. 12, 51-60
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The role of charged residues mediating low affinity protein-protein recognition at the cell surface by CD2
Davis SJ, Davies EA, Tucknott MG, Jones EY, van der Merwe PA. (1998), Proc Natl Acad Sci U S A. 95, 5490-4
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The structure and ligand interactions of CD2: implications for T-cell function
Davis SJ, van der Merwe PA. (1996), Immunol Today. 17, 177-87
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Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2
Davis SJ, Puklavec MJ, Ashford DA, Harlos K, Jones EY, Stuart DI, Williams AF. (1993), Protein Eng. 6, 229-32
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Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2
Jones EY, Davis SJ, Williams AF, Harlos K, Stuart DI. (1992), Nature. 360, 232-9
