Ricardo Fernandes
Ricardo studied for his PhD under Simon’s supervision and found the lab – and the wider environment of the WIMM – an inspiring place to study.
The approach to science at the lab – and how to design experiments that fully answer your questions – gave Ricardo an excellent grounding for his PhD and subsequent work.
He also valued the technical input from the support staff, especially the four research assistants.
“There’s a great atmosphere in the lab. Everyone helps you when you arrive; they help you get going.” – Ricardo.
Ricardo particularly enjoyed the collaborative environment of the WIMM and the opportunity to discuss and learn from the different research groups.
For him, it provided the ideal opportunity to meet up with other students and researchers in other fields in a relaxed setting and discuss scientifically good work.
As a direct result of his work with Simon, Ricardo won a Wellcome Fellowship. This is no small achievement, only eight or nine are awarded to every 1000 applicants, and two have been awarded to PhD students from the Davis Lab, Oxford.
Top Ten Papers
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A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer
James JR, Oliveira MI, Carmo AM, Iaboni A, Davis SJ. (2006), Nat Methods. 3, 1001-6
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Crystal structure of a soluble CD28-Fab complex
Evans EJ, Esnouf RM, Manso-Sancho R, Gilbert RJ, James JR, Yu C, Fennelly JA, Vowles C, Hanke T, Walse B, Hünig T, Sørensen P, Stuart DI, Davis SJ. (2005), Nat Immunol. 6, 271-9
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The T cell surface – how well do we know it?
Evans EJ, Hene L, Sparks LM, Dong T, Retiere C, Fennelly JA, Manso-Sancho R, Powell J, Braud VM, Rowland-Jones SL, McMichael AJ, Davis SJ. (2003), Immunity. 19, 213-23
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The interaction properties of costimulatory molecules revisited
Collins AV, Brodie DW, Gilbert RJ, Iaboni A, Manso-Sancho R, Walse B, Stuart DI, van der Merwe PA, Davis SJ. (2002), Immunity. 17, 201-10
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LICOS, a primordial costimulatory ligand?
Brodie D, Collins AV, Iaboni A, Fennelly JA, Sparks LM, Xu XN, van der Merwe PA, Davis SJ. (2000), Curr Biol. 10, 333-6
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Structure and dimerization of a soluble form of B7-1
Ikemizu S, Gilbert RJ, Fennelly JA, Collins AV, Harlos K, Jones EY, Stuart DI, Davis SJ. (2000), Immunity. 12, 51-60
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The role of charged residues mediating low affinity protein-protein recognition at the cell surface by CD2
Davis SJ, Davies EA, Tucknott MG, Jones EY, van der Merwe PA. (1998), Proc Natl Acad Sci U S A. 95, 5490-4
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The structure and ligand interactions of CD2: implications for T-cell function
Davis SJ, van der Merwe PA. (1996), Immunol Today. 17, 177-87
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Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2
Davis SJ, Puklavec MJ, Ashford DA, Harlos K, Jones EY, Stuart DI, Williams AF. (1993), Protein Eng. 6, 229-32
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Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2
Jones EY, Davis SJ, Williams AF, Harlos K, Stuart DI. (1992), Nature. 360, 232-9
